To destroy the organic texture and vital functions of; to produce gangrene in.
- To cause to experience shame, humiliation, or wounded pride; humiliate.
- To discipline (one's body and physical appetites) by self-denial or self-inflicted privation.
- To practice ascetic discipline or self-denial of the body and its appetites.
- Pathology To undergo mortification; become gangrenous or necrosed.