To dispose or incline beforehand; to give a predisposition or bias to; as, to predispose the mind to friendship.
- To make (someone) inclined to something in advance: His good manners predispose people in his favor. See Synonyms at incline.
- To make susceptible or liable: conditions that predispose miners to lung disease.
- Archaic To settle or dispose of in advance.
- To provide an inclination or susceptibility: a genetic trait that predisposes to the development of cancer.